Research Interests

  • Leishmania
  • Developing chimeric DNA Vaccine against Leishmaniasis and Tuberculosis.
  • Screening and selection of novel anti-leishmanial active compounds against leishmania from Indian herbs.
  • Development of indigenous PCR and serodiagnostic kits for human & animal toxoplasmosis.
  • Molecular Epidemiology and development of VL and PKDL specific PCR primers.
  • Tuberculosis
  • Elucidating the drug resistance mechanism of M. tuberculosis using genomic, proteomic and bioinformatics strategies.
  • Identification and characterization of novel proteins / antigens for serodiagnosis of multi drug resistance tuberculosis.
  • Analyzing the genomic architecture of ABC transporters of M. tuberculosis and M. avium subsp. paratuberculosis through bioinformatics methods.
  • Developing mono and multiplex PCR system for species specific identification of different mycobacterial species.
  • Lineage analysis of M. tuberculosis and contact investigation in household contacts through various molecular genotypic tools.
  • Sequence based Genotyping of mycobacteria isolated from various clinical sites in HIV positive and negative patients.
  • Virology
  • Revaluation of NASBA-Nuclisens methods with in-house real time PCR methods and HIV and HSV viral load monitoring.
  • Prevalence of HBV, HCV and various HHVs in tertiary care hospital setting.
  • HHVs as co-pathogens in HIV progression and transmission.
  • The role of TNF-alfa and IFN-gama and the success of Anti-tubercular therapy in Immune Reconstitution Disease in HIV/TB coinfected patients .
  • HBV mutation studies.
  • Other
  • Developing a novel multiplex PCR system for simultaneous detection and differentiation of Salmonella, Giardia lamblia, Entamoeba histolytica, Hepatitis A & E directly from drinking water samples.

Contact Me

Professor & Head
Division of Clinical Microbiology & Molecular Medicine,
Department of Laboratory Medicine,
All India Institute of Medical Sciences
New Delhi-110029, India
Ph: (+91-11) 2658-8484 / 2659-4977
Fax: (+91-11) 2658-8663/ 2658-8641
Cell No: (0)9810813435
Email: sarman_singh@yahoo.com
ssingh56@hotmail.com